BISE Hyderabad Board was wholly established in 1961. Initially, examinations of HSSE and SCC were under Sindh University. Moreover, in the beginning, BISE Hyderabad was only responsible for the Matric examination. Most importantly, in no time, it took a great place in Sindh Boards. Further, all boards except Karachi Board were under BISE Hyderabad. Moreover, after the National Education Commission, it started two years program of Intermediate, specifically. Importantly, it took its complete independence in 1961. Firstly, it was situated in a small building. And then it moved to Latifabad Unit 9, Hyderabad.